A transparent colorless or slightly yellow solution for injections, produced in glass vials of 5, 10, 20, 30, 50, 100, 200 and 250 ml.
1 ml of FLEXOPROFEN« 2,5% injection solution contains 25 mg of ketoprofen.
1 ml of FLEXOPROFEN« 5% injection solution contains 50 mg of ketoprofen.
1 ml of FLEXOPROFEN« 10% injection solution contains 100 mg of ketoprofen.
Ketoprofen, an active substance of FLEXOPROFEN«, possesses anti-inflammatory, analgetic, and antipyretic properties and is effective for treatment of acute, sub-acute and chronic inflammations accompanied by the symptom of pain. The mechanism of action lies in the suppression of the prostaglandin synthesis by interrupting the arachidonic acid metabolism. After intramuscular injection the maximum content of ketoprofen in the blood plasma is reached in 30 minutes. The bioavailability of FLEXOPROFEN« varies from 85% to 100%. Ketoprofen is effused from the organism primarily through kidneys.
In the recommended dosage the drug does not produce the sensibilizing effect and is not accumulated in the organism.
- Treatment of inflammatory diseases of musculoskeletal system (arthritis, arthrosis, dislocation, synovitis, tendinous synovitis, etc.), pain syndromes of various etiology (traumatic and postsurgical pain, gripes), as well as hyperthermia of horses, calves, dogs and cats.
. Horses: intravenous injection of 2.2 mg/kg of the active substance once a day, during 1 to 5 days. Calves: intravenous and intramuscular injection of 3 mg/kg of the active substance once a day during 1 to 5 days. Dogs, cats: subcutaneous, intramuscular, intravenous injection of 2 mg/kg of the active substance once a day during 1 to 5 days.
FLEXOPROFEN« should not be used in case of allergy to ketoprofen and similar substances, gastric and duodenal ulcer, hemorrhagic syndrome, pronounced hepatic and renal failure or pregnancy.
FLEXOPROFEN« should not be used in combination with other nonsteroid anti-inflammatory agents, glucocorticoids and anticoagulating agents. It should not be mixed with other drugs in the same syringe.
Calves slaughter and butchering is allowed only 5 days after the last administration of the drug. The meat of animals slaughtered prior to the expiry of the indicated period can be used for animal feeding or for production of tankage.
FLEXOPROFEN« should be stored with precaution (List B) at 0 to 25 °C in a dry place away from direct light. Validity period in prescribed conditions ľ 3 years from the date of production.